Alberta study shows reduced neural activity in zebrafish exposed to THC, CBD or both

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Still, more work is needed to better understand the mechanism behind the effects on neural activity, Ali says, suggesting prospective parents may want to limit exposure to the compounds as they would with nicotine and alcohol. Zebrafish exposed to THC in the earliest stages of their development saw a 70 per cent dive in neural activity later in life and the decrease, at over 70 per cent, was starker when they were immersed in CBD, the University of Alberta reports. Ali suggests prospective parents may want to limit exposure to the compounds as they would with nicotine and alcohol. / At higher doses, the study shows both cannabinoids could dramatically reduce neural activity and locomotor activity, the abstract states. Developing zebrafish embryos were left to incubate for 10 hours in a solution containing THC, CBD or a combination of the two immediately after fertilization. Ten hours is enough time for a zebrafish to reach a stage of development when multiplying cells start to form multiple tissue layers.

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Zebrafish exposed to THC in the earliest stages of their development saw a 70 per cent dive in neural activity later in life and the decrease, at over 70 per cent, was starker when they were immersed in CBD, the University of Alberta reports.

If the same thing happens with humans, the researchers suggest that the findings could have implications for prenatal development in humans, an article posted on the university’s website notes.

“In light of legislative changes and the widespread use of cannabis...

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